HRT - Why is there a shortage and which medications are affected?

Published: 12th August 2019

Why is there a HRT shortage?

The reasons for this are unclear; there has been some blame on Brexit, some have blamed manufacturing issues, and there has also been an increase in the prescribing of hormone replacement therapy (HRT) recently.
 

Which types of HRT are affected?

The types of HRT affected by this shortage are mostly various tablet forms of combination preparations containing estrogen and a type of progestogen. Some combination patches are also affected.

This shortage can actually be used as an opportunity to review the dose and type of HRT you are taking and decide whether this needs to be changed and even improved upon. If you're having trouble sourcing HRT from your usual pharmacy, it can be worth trying an online supplier as these often stock a broader range of medications.
 

What is HRT? 

hrt stock shortages

There are many different types and doses of HRT available, so it is really important to be given the right one for you.

All types of HRT contain oestrogen, which works to replace the oestrogen that your ovaries no longer makes after the menopause. Taking HRT can really improve your symptoms (and quality of life) and also lead to a greater improvement in your heart and bone health. The best time to start HRT is when your periods are changing and you experience symptoms (i.e. when you are perimenopausal).
 

Is HRT safe?

HRT is actually much safer than most people realise. For the vast majority of women, the benefits of HRT outweigh the risks. More information about HRT is available here - and body identical HRT here
 

What type of HRT should I take?

There is now robust evidence which shows that taking body identical HRT derived from the yam (a root vegetable) is the best type of HRT for most women. I have written an Easy HRT Prescribing Guide which many GPs tell me they find really useful. Numerous women have told me they have printed this out and given it to their GPs too.
 

What form of HRT should I use?

There are many advantages of using the oestrogen as a patch of gel instead of a tablet and having the progestogen as micronised progesterone oral capsule (Utrogestan in the UK) or having a Mirena coil.

The oestrogen that I usually prescribe for women is called 17 beta-estradiol. This is a 'body identical' oestrogen, so has the same molecular structure as the oestrogen in our bodies before the menopause.

It is safer to have the oestrogen as a patch or gel, as this is absorbed directly through our skin into our bloodstream and has less side effects and risks. These types of oestrogen can be given to women who suffer with migraines and those with a higher risk of blood clot.

There is a very small risk of clot with taking oestrogen as a tablet. For most women their risk of clot is low, so this increase does not put them at undue risk, but many doctors are now preferring to prescribe patches or gels.

The type of progestogen (needed for women who have their womb) I usually recommend is called 'micronised' progesterone (Utrogestan). This is a 'body identical' progestogen as it has the same molecular structure as the progesterone in our bodies. This means it is usually associated with fewer side effects than other types of progestogens. Side effects of older progestogens can include bloating, weight gain, spots and mood swings.

The additional advantage of micronised progesterone is there is no increased risk of breast cancer for the first five years of taking it. After this time the risks of breast cancer are very low and seem to be lower than the risk for a woman taking the older types of progestogen. However, even with other types of combined HRT the risk of breast cancer is extremely low. Women who are overweight or drink around a couple of glasses of wine a night actually have a greater risk of breast cancer than women taking combined HRT.
 

Why won't my doctor prescribe HRT?

hrt shortage uk

Despite all the national and international menopause guidelines clearly stating that most women benefit from taking HRT - and the fact that the risks with taking HRT are very low - many women still find that their GPs are refusing to give them HRT.

A recent survey I undertook of nearly 2,000 women found that 66% of women have inappropriately been given or offered antidepressants. There is no evidence that antidepressants improve the low mood associated with the perimenopause and menopause.

If you have had a negative experience obtaining HRT and do not feel confident approaching your GP then this letter may help you. This has been used with success by many women who are struggling with their GP prescribing HRT.

I am hoping the shortage of HRT can be a positive experience to learn new facts about HRT and be given the right type for you.


Newson Health Menopause and Wellbeing Centre was founded by leading menopause specialist and GP, Dr Louise Newson, and officially opened in September 2018 by Liz Earle MBE. Created to help women receive the most appropriate, individualised treatment for their perimenopause and menopause, it has quickly become a centre of excellence, providing care to women of all ages, as well as running educational events for primary care clinicians.

Dr Newson is also the founder of the Menopause Doctor website, a free resource since 2017, providing the latest unbiased, evidence based information about the menopause and perimenopause for women as well as the most recent national and international menopause articles and guidelines for healthcare professionals.

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